Molecular Mechanisms of Cancer
Cancer is a term used to define over 200 subtypes of diseases all with the ability to divide uncontrollably. While these varied subtypes are identified by their place of origin or the tissues they affect, their most distinct features are the underlying signaling cascades that drive the disease. This course will discuss the roles of tumor suppressors and oncogenes in tumor growth at the molecular level. It will also explore in detail exemplar pathways that are disrupted in cancer as well as how such knowledge translates to novel therapies. Throughout, the course aims to provide a framework for how molecular mechanisms function and the important role they play in human biology.
- Define tumor suppressors and oncogenes and their respective roles along with examples.
- Gain an understanding of important molecular pathways in cells and how they are affected in cancer.
- Understand how cancer cells hijack various signaling cascades to drive different aspects of malignancy.
- Develop a theoretical and practical framework on the applicability of this knowledge in therapeutic interventions.